It begins:

Dan Neary oversees Facebook Inc. ’s advertising operations across Asia-Pacific, a fast-growing region that is home to some of the social network’s biggest markets.

Nearly all of Facebook’s revenue—some $3.2 billion as of the third quarter—comes from fees companies pay to show users ads.

As the Menlo Park, Calif.-based company continues to add to its 1.35 billion monthly active users globally, many are coming from emerging Asian countries such as Indonesia and India.

Moreover, such users are accessing the platform not just on PCs, but increasingly on mobile devices, presenting new challenges and opportunities for Facebook and advertisers.

Mr. Neary, a 49-year-old Chicago native who began his career at Kellogg Co. before holding senior positions at Skype and eBay Inc., is tasked with ensuring the company continues to profit in an ever-changing technological environment.

In a recent interview at Facebook’s offices in Singapore, Mr. Neary discussed the shift to mobile, as well as what Facebook’s photo-sharing service Instagram and messaging app WhatsApp can contribute to the company.

Mr. Neary was cautious in addressing Founder and Chief Executive Mark Zuckerberg ’s October visit to China and possible expansion there, saying only that having access to the country’s 1.3 billion people is an important part of Facebook’s future growth plan.

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You may recall that some of my similar interviews in the past — part of our “Boss Talk” series — include chats with BlackBerry Chief Executive John Chen; Twitter’s vice president of Asia Pacific, the Americas and emerging markets, Shailesh Rao; and Evernote Chief Executive Phil Libin.